Which of the following infectious diseases pose a pandemic threat according to public health guidelines?

The rationale for selecting all of the options is based on the understanding that each of the infectious diseases mentioned has demonstrated the potential to spread globally and significantly impact public health.

Influenza is a well-known pandemic threat due to its ability to mutate rapidly, leading to new strains that can infect large populations quickly. Historical pandemics, such as the 1918 Spanish flu, illustrate the virus's capacity to cause widespread illness and death.

Ebola virus, while more localized, is recognized by public health authorities for its potential to cause outbreaks that could escalate into pandemics if not properly controlled. The high fatality rate of Ebola underscores the urgency of monitoring and controlling its spread.

SARS-CoV-2, the virus responsible for COVID-19, clearly demonstrated its pandemic potential by rapidly spreading worldwide, overwhelming healthcare systems and resulting in significant morbidity and mortality rates. Its ability to spread person-to-person in various settings has positioned it as a key concern for public health.

Each of these diseases has characteristics that require vigilant surveillance, preparedness, and response strategies to mitigate their potential impact on global health.